A 3-month, double-blind, controlled trial of feeding with sucrose polyester in human volunteers

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A 3-month, double-blind, controlled trial of feeding with sucrose polyester in human volunteers.

Sucrose polyester (SPE) is a tasteless, odourless substance which reduces plasma cholesterol concentrations and may therefore be valuable as a fat substitute in human foodstuffs. It has recently been approved for use in snack foods by the United States Federal Drug Administration. The current study was designed to investigate its effects on gastrointestinal physiology and nutrient absorption in...

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Sucrose polyester in human volunteers.

The recent publication by Kelly et al. (1998) of their study on sucrose polyesters (SPE) raised concerns about the possible gastrointestinal (GI) and nutritional effects of olestra. These concerns were echoed in the popular press (‘Doubts raised over anti-obesity fat substitute’. The Times, 11 August 1998.). Olestra’s potential to cause GI and nutritional effects has been carefully reviewed by ...

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ژورنال

عنوان ژورنال: British Journal of Nutrition

سال: 1998

ISSN: 0007-1145,1475-2662

DOI: 10.1017/s0007114598001755